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DOI: 10.21045/2071-5021-2017-55-3-8
Lazarenko V.A., Antonov A.E.
Kursk State Medical University, Kursk, Russia
Contacts: Andrey E. Antonov,
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Information about authors:
Lazarenko V.A., http://orcid.org/0000-0002-2069-7701
Antonov A.E., http://orcid.org/0000-0001-5745-3586
Acknowledgments.The study had no sponsorship.
Conflct of interests. The authors declare no conflict of interest.
Abstract. Significance of studying bad habits as
a risk factor for pancreatitis is substantiated by high morbidity with a
tendency towards further growing both in Russia and throughout the
world; high lethality in case of destructive forms of the disease as
well as rapidly changing living conditions of the modern society.
The purpose of the work was to study the current
situation with tobacco smoking and alcohol abuse as risk factors for
pancreatitis and specify relevant measures for prevention.
Methods. The study is based on applying methods of
descriptive statistics, correlation and regression analysis of data
collected on 167 patients undergoing in-patient treatment in hospitals
of the city of Kursk for acute and chronic pancreatitis.
Results. The obtained correlation values demonstrate
that duration of smoking has a greater effect on the severity at
admission and duration of the disease (ηxy = 0.28, p <0.05 and ηxy = 0.61, p <0.001, respectively) in comparison with duration of alcohol abuse (ηxy = 0.24, p> 0.05 and ηxy = 0.49, p <0.001).
The age of onset of smoking has also a greater impact on the severity at admission and duration of the disease (ηxy = 0.43, p<0.001 and ηxy = 0.26, p<0.05) in comparison with the similar parameter characterizing alcohol abuse (ηxy = 0.25, p <0.01 and ηxy = 0.24, p <0.01, respectively).
The regression analysis results let us assume that duration of
smoking demonstrates a double effect on quantitative parameters of
health – a cumulative and an indirect one via progressive increase in
the number of cigarettes smoked per day.
Conclusions. 1. Significant prevalence of bad habits
was identified in patients with pancreatitis. 70.3% (m = 5.31) of male
and 19.4% (m = 4.1) of female patients abused alcohol, while smoking was
confirmed in 79.7% (m = 4.7) of men and 8.6 % (m = 2.9) of women.
2. The greatest impact on the severity level at admission was associated with the following factors: “age of onset of smoking” ηxy = 0.43 (p <0.001), and “duration of smoking” ηxy
= 0.28 (p <0.05). Tobacco smoking prevention as a set of measures
for controlling pancreatitis and its consequences is mostly expedient in
boys, adolescent girls and adults aged 20–23 years and over.
Scope of application. The study results can be
used for developing preventive measures aimed at braking bad habits to
be implemented by health and education facilities.
Keywords. Pancreatitis; abdominal surgery; risk factors; smoking; alcohol abuse; bad habits.
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