Tsybikova E.B.
Federal Research Institute for Health Organization and Informatics, Ministry of Health of the Russian Federation, Moscow

Contacts: Erzheny Tsybikova, This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Abstract. Background. The first decade of the 21st century was characterized by substantial growth of patients with TB/HIV co-infection. The number of regions of the Russian Federation with high prevalence of TB/HIV co-infection doubled since 2000 and reached 43 regions representing five largest Russian federal districts.

Irregular prevalence of TB/HIV co-infection in the Russian regions affects quality management of TB-control measures reducing their efficiency.

The purpose is to study epidemiology of TB/HIV co-infection in Russia in the beginning of the 21^st century (2004-2013).

Methods and data: data from official statistical forms ## 8, 33 and 61 received from TB dispensaries of the 83 regions of the Russian Federation for 2011. Analysis was conducted using correlation analysis.

Results. Analysis of TB/HIV co-infection morbidity in Russia in 2004-2013 showed that the number of such patients is growing presumably due to HIV patients.

Dynamics of TB/HIV co-infection prevalence in Russia in 2004-2013 represents an upward trend with a cumulative growth rate in 2013 adding up to 777% compared to 2004.

Growth is mainly observed in young age groups: 25-34 and 35-44 years.

The share of TB patients died from HIV-infection in those age groups equals to 86% out of the total number of TB deaths in these age groups.

The share of patients with tuberculosis meningitis in 2013 in the age groups of 25-34 and 35-44 added up to 70% of the total number.

Results of the correlation analysis show that differences in mortality rates among newly detected TB cases in the 83 Russian regions are determined by mortality due to HIV-infection and co-morbidities rather than TB mortality.

Keywords: TB/HIV co-infection; morbidity; mortality; meningitis; correlation analysis.

References

1. Lechenie tuberkuleza: rekomendatsii. 4-e izdanie [Treatment of tuberculosis: recommendations. 4-th ed.]. Geneva: WHO Regional office for Europe. 2011. 183p. [Online] Available from: http://whqlibdoc.who.int/publications/2011/9789244547830_rus.pdf (In Russian).
2. Mezhdunarodnaya statisticheskaya klassifikatsiya bolezney i problem, svyazannykh so zdorov'em. Desyatyy peresmotr [International statistical classification of diseases and relates health problems. 10-th revision]. Geneva: VOZ; 1995. 179 p. (In Russian).
3. Pokrovskiy V.V., Ladnaya N.N., Savchenko I.G. Epidemiya VICh-infektsii v Rossii [Epidemic of HIV infection in Russia]. Epidemiologiya i infektsionnye bolezni 1998 (5): 4-11. (In Russian).
4. Tsybikova E.B. Ispol'zovanie metoda matrichnogo analiza dlya otsenki potrebnosti v okazanii khirurgicheskoy pomoshchi vpervye vyyavlennym bol'nym s destruktsiey legochnoy tkani v sub"ektakh Rossiyskoy Federatsii [Implantation of matrix analysis to assess the need in surgical care in newly diagnosed patients with destruction of lung tissue in the subjects of the Russian Federation]. Sotsial'nye aspekty zdorov'ya naseleniya [serial online] 2014 [cited 2014 Mar 18]; 35 (1). Available from: http://vestnik.mednet.ru/content/view/546/30/ (In Russian).
5. Gandhi N.R., Moll A., Sturm A.W., Pawinski R., Covender T., Lalloo U., Zeller K., Andrews J., Friedland G. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet. 2006; 368 (9547): 1575-1580.
6. Harries A.D., Zachariah R., Lawn S.D. Providing HIV care for co-infected tuberculosis patients: a perspective from sub-Saharan Africa. International Journal of Tuberculosis and Lung Disease. 2008 (12): 39-43.
7. Lawn S.D., Churchyard G. Epidemiology of HIV-associated tuberculosis. Current Opinion in HIV and AIDS. 2009 (4): 325-333.
8. Pandey KD, Roy G, Kumar G, Saurabh S, Agarval DK. Diagnosis and treatment of pulmonary tuberculosis in patients with HIV. The Lancet Infectious Diseases. 2012; 12 (4): 267.
9. Uyei J, Coetzee D, Macinco J, Guttmacher S. Integrated delivery of HIV and tuberculosis services in sub-Saharan Africa: a systematic review. The Lancet Infectious Diseases. 2011; 11 (11): 855-867.

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