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Main arrow Archive of previous Issues arrow ╣5 2012 (27) arrow Epidemiological indicators of tuberculosis combined with HIV-infection
Epidemiological indicators of tuberculosis combined with HIV-infection Print
Thursday, 13 December 2012

E.B. Tsybikova
Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian Federation, Moscow

Summary. Background. In the first decade of the XXI st century, an overall spread of tuberculosis combined with HIV-infection (co-infection) was evidenced in Russia, and this has urged a new tide of growing morbidity and mortality as concerns both nosologies.

Aim of the study: to identify and evaluate certain epidemiologic indicators for scoring the scale of spread of the aforementioned co-infection at the level of Constituent Territories of the Russian Federation.

Materials and Methods: Functioning indicators for tuberculosis and for HIV-infection for 2000-2011 were implemented for this analysis. The grade of spread of co-infection was established for 83 Constituent Territories of Russia. The techniques of ranging these CT along the aforementioned indicators and co-indicators was implemented. Correlation analysis was used. Coefficients of Pearson were calculated. Coefficient of correlation was significant when exceeding 0.21 (n=81). A significance level of less than 0.05 (p) was used. Established variables were used for evaluation of the magnitude of an error.

Results: Significant spread of HIV-infection among TB patients was identified only in 43 Constituent Territories of the Russian Federation (53% of their total number), while wide-spread TB among HIV-infected patients was significant in all Constituent Territories without any exception. Quite a row of epidemiological factors common for both nosologies were identified in this study enabling the formation of a unified specific cohort of patients aged 25-34 being appropriate for regular co-infective prevention follow-up for detection of either TB- or HIV-infection , accordingly, depending on the primary case. Correlation analysis showed close relationship between primarily identified patients with meningitis tuberculosa and co-infective patients. The more was the proportion of HIV-infection in TB patients, the more was incidence of meningitis tuberculosa registered.

Conclusion: Significant spread of HIV-infection among TB patients was identified only in 43 Constituent Territories of the Russian Federation (53% of their total number), while wide-spread TB among HIV-infected patients was significant in all Constituent Territories without any exception. There was performed the formation of a unified specific cohort of male patients only aged 25-34 being appropriate for regular co-infective prevention first-line follow-up for detection of either TB- or HIV-infection , accordingly, depending on the primary case. It was meningitis tuberculosa that was used as a marker of co-infection.

Keywords. Epidemiologic nosology indicators; tuberculosis combined with HIV-infection; disease revelation/identification; disease wide-spread; meningitis; correlation analysis.

References

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