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Main arrow Archive of previous Issues arrow ╣5 2013 (33) arrow Organization of tuberculosis treatment in russian prisons in 2012: current situation and resources to improve effectiveness
Organization of tuberculosis treatment in russian prisons in 2012: current situation and resources to improve effectiveness Print
Tuesday, 12 November 2013

S.A. Sterlikov1, S.N. Vorobey2, V.E. Odintsov2, A.V. Gazheva1
1Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian Federation, Moscow
2Department of Medical and Sanitary Care, Federal Penitentiary Service of Russia, Moscow

Summary. Background. Analysis of unfavorable outcomes of TB treatment in prisons helps to develop measures to improve treatment effectiveness which is crucial for improving tuberculosis epidemic situation in general.

The aim of the study was to review problems related to treatment of patients with tuberculosis in prisons and develop possible solutions.

Methods. A prospective cohort study of treatment outcomes of 16,922 patients with pulmonary tuberculosis, including 11,300 new cases, 3,979 relapse cases and 1,649 other cases of re-treatment. Causes for low effectiveness of TB treatment have been analyzed based on the sample of 541 new smear positive pulmonary cases in prisons in 18 regions of Russia that met the quality criteria of cultural diagnostics and with the share of transferred out less than 20%.

Results. In 75.6% of cases (97.1% among new cases) chemotherapy regimens with first-line drugs were used. In 2011, 56.5% of new cases cured and completed, while 10.8% failed. 5.3% of patients continued treatment for multidrug resistant tuberculosis, 2.5% died, 3.5% defaulted and 21.4% transferred out.

Sample review of treatment results in 18 regions showed that the main cause of unfavorable outcomes (42.4%) is multi-drug resistant tuberculosis (MDR-TB). The outcome of "transferred out" accounted for 20.4% of unfavorable outcomes. Other causes were less common. Treatment effectiveness of relapse cases was 45.0% and 25.3% for other courses of re-treatment; decreased treatment effectiveness is due to early termination of treatment.

Conclusion. Treatment effectiveness among new cases decreases primarily due to multiple drug resistance, while treatment effectiveness among re-treatment cases decreases due to lack of compliance to treatment. To improve patient compliance actions aimed at developing motivation for treatment adherence should be intensified.

Scope of application. Prisons in Russia.

Keywords: tuberculosis in prisons; organization of treatment of patients with tuberculosis; outcomes of TB treatment in prisons; TB treatment effectiveness; multiple drug resistance.


  1. Bogorodskaya EM, Danilova ID, Lomakina OB. Formation of incentives for recovery and adherence to chemotherapy in tuberculosis patients. Manual for physicians. ╠., 2006. 44 p. (In Russian).
  2. Nechaeva OB, Eysmont NV. The impact of HIV infection on TB epidemic situation in the Russian Federation. Sotsial'nye aspekty zdorov'ya naseleniya [Online Scientific Journal] 2011; 19 (3). [cited 2013 Jul 25]. Available from: http://vestnik.mednet.ru/content/view/315/30/lang,ru/ (In Russian).
  3. Sector indicators of TB control in 2008-2009. Statistical documents. Tver': "Triada" Publishing House, 2010. 60 p. (In Russian).
  4. Sector indicators of TB control in 2009-2010. Statistical documents. ╠oscow. 2011. 60 p. (In Russian).
  5. Sector indicators of TB control in 2010-2011. Analysis of the main indicators and management decisions. ╠oscow. 2012. 81 p. (In Russian).
  6. "On approving the list of health care and health correctional facilities of the penitentiary system to provide medical care to prisoners", the Order of the Ministry of Justice of 2006 Aug 16 ╣ 263. [Internet] 2006 [cited 2013 Jul 25]. Available from: http://bestpravo.ru/rossijskoje/kz-pravila/l9p.htm (In Russian).
  7. Calculation of indicators for registration and treatment of TB patients with using a cohort analysis. Methodical recommendations. ╠oscow. 2008. 24 p. (In Russian).
  8. "On approving the state public health policy": the Decree of the President of the Russian Federation of 2012 May 7 ╣ 598. [Internet] 2012 [cited 2013 Jul 25]. Available from: http://www.rg.ru/printable/2012/05/09/zdorovje-dok.html (In Russian).
  9. Shilova MV. Tuberculosis in Russia in 2010. ╠oscow. 2012. 224 p. (In Russian).
  10. Aerts A, Habouzit M, Mschiladze L, Malamadze N., Sadradze N., Menteshashvili O, et all. Pulmonary Tuberculosis in Prisons of the Ex-USSR State Georgia: Results of a nation-wide preşvalence survey among sentenced inmates. International Journal of Tuberculosis and Lung Disease 2000; 4(12): 1104ľ1110.
  11. Assefzadeh M, Barghi RG, Shahidi ShS. Tuberculosis case-finding and treatment in the central prison of Qazvin province, Islamic Republic of Iran. East Mediterr Health J 2009; 15(2): 258-263.
  12. Coninx R, Mathieu C, Debacker M, Mirzoev F, Ismaelov A, de Haller R, et all. First-line tuberculosis therapy and drug-resistant Mycobacterium Tuberculosis in prisons. Lancet 1999; 353: 969-973.
  13. Cummings KC, Mohle-Boetani J, Royce SE, Chin DP. Movement of tuberculosis patients and the failure to complete antibacterial treatment. Am. J. of Respiratory and Critical Care Medicine 1998; 157 (4): 1249-1252.
  14. Hasker E, Khodjikhanov M, Usarova S, Asamidinov U, Yuldashova U, J van der Werf M, et all. Default from tuberculosis treatment in Tashkent, Uzbekistan; Who are these defaulters and why do they default? BMC Infectious Disease 2008; 8: 97
  15. Marco A, Cayla JA, Serra M, Pedro R, Sanrama C, Guerrero R, et all. Predictor of adherence to tuberculosis treatment in a supervised therapy programme for prisoners before and after release. Study Group of Adherence to Tuberculosis Treatment of Prisoners. European Respiratory Journal 1988; 12(4): 967-971.
  16. Minisi T, Tumo J, Govender I. Factors associated with pulmonary tuberculosis outcomes among inmates in Potchefstroom Prison. South Afr J Epidemiol Infect 2013; 28(2): 96-101.
  17. OĺGrady J, Hoelscher M, Atun R, Bates M, Mwaba P, Kapata N, et all. Tuberculosis in prisons in sub-Saharan Africa - the need for improved health services, surveillance and control. Tuberculosis (2011), doi:10.1016/j.tube.2010.12.002
  18. Valway SE, Greifinger RB, Papania M, Kilburn JO, Woodley C, DiFerdinando GT, et all. Multidrug-resistant tuberculosis in the New York State prison system, 1990-1991. J Infect Dis 1994; 170(1): 151-156.

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