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Tuesday, 06 March 2018

DOI: 10.21045/2071-5021-2018-59-1-9

1Ruselevich M.V., 1Malikova L.M., 1Komarov S.G., 2Kharina D.V.
Institute of Advanced Training, Federal Medical and Biological Agency, Moscow, Russia
State Research Center of the Russian Federation, Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency, Moscow

Contacts: Kharina Daria, e-mail: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Acknowledgments. The study had no sponsorship.
Conflict of interests. The authors declare no conflict of interest.


Significance. Respiratory allergic diseases have recently become not only a medical but also a social problem. On the one hand, there is a continuous trend towards disease aggravation in childhood, on the other hand ľ its prevalence is on the rise. Growing incidence of allergic diseases, their aggravated course, their significant impact on the development and course of chronic nonspecific inflammatory diseases of various sites makes investigation of this pathology a priority among other modern health care problems.

Purpose: to analyze medical and social factors affecting formation of respiratory allergic diseases of pollen etiology in children in the modern context.

Methods. To study impact of medical and social factors on respiratory allergic diseases of pollen etiology two groups of children were selected. The main group (I) consisted of 255 children who were under allergologistĺs follow-up due to respiratory allergic disease. The control group (II) also consisted of 255 children who were under pediatricianĺs follow-up in Moscow children's polyclinics and attended schools or preschool facilities.

To process study materials standard statistical methods were applied.

Results. Direct correlation between motherĺs non-employment in the production industry and respiratory allergic disease in her child (I=3.17) was identified. About 15% of working women are exposed to occupational hazards; about one third of them were exposed to occupational hazards prior to delivery.

Direct correlation was found between respiratory allergic disease in a child and hereditary load in both parents (I=4.7), and in mother only (I=3.8).

Conclusions. 1. Correlation analysis of factors accompanying respiratory allergic diseases of pollen etiology in children, showed their different significance.

2. Among the variety of medical, biological, social hygienic and psychological factors the authors managed to detect a small share of factors that are directly related to the development of respiratory allergic diseases in children (significance test (r)>20%): hereditary load in both parents (r=40%); hereditary load in mother (r=36.4%); early toxicosis during pregnancy (r=24.8%); early toxicosis and gestosis in pregnancy (r=45.0%).

Keywords: medical and social factors; respiratory allergic diseases; pollen etiology; gestational age; childhood; diseases of the respiratory system.


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