About this Journal Publication ethics Editorial Board Editorial Council Editorial Office For the Authors Contacts

News feeds

Journal in Databases


Google Scholar

Google Scholar

For authors' attention

Publication is free of charge

In aims to provide interconnection of publications in international scientific journals using Digital Object Identification - DOI, our editorial office incorporated the journal "Social aspects of population health" into international reference system CrossRef.

Since 2016 DOI will be assigned to all scientific articles published in our journal free of charge.

Also DOI will be assigned to all articles published in 2014 and 2015 free of charge as well
Main arrow Archive of previous Issues arrow 2 2013 (30) arrow Use of matrix analysis to evaluate epidemiological situation with hiv-tb co-infection in constituent entities of Russia
Use of matrix analysis to evaluate epidemiological situation with hiv-tb co-infection in constituent entities of Russia Print
Thursday, 18 April 2013

Summary. Pulmonary tuberculosis and HIV infection are currently widespread in all regions of Russia with uneven incidence of tuberculosis and HIV-infection that is subject to significant fluctuations.

Objective: to review epidemiological situation with HIV-TB co-infection in Russian regions with the use of matrix analysis to determine inputs each infection contributes to the epidemiological process.

Methods: indicators of pulmonary tuberculosis and HIV-infection for 2010 have been used. To develop the matrix 81 regions of Russia have been rated according to their rates of HIV prevalence. Groups with highest and lowest incidence of pulmonary tuberculosis and HIV-infection have been compared.

Results: high prevalence of pulmonary tuberculosis in all regions of Russia is the main prerequisite for HIV-TB co-infection nowadays. Against the background of a widespread prevalence of HIV infection a sharp rise in HIV-TB co-infection in regions with high incidence of HIV infection becomes a matter of a great concern.

The Russian tuberculosis facilities are urged to introduce a closed treatment regiment with isolation of tuberculosis patients with sputum smear-positive pulmonary tuberculosis. Matrix analysis helps to evaluate relations between the two infections in the Russian regions and choose priorities for developing organizational measures to control HIV-TB co-infection.

Conclusions: While the incidence of pulmonary tuberculosis in all regions of Russia in 2010 was over 35 per 100,000 population, the incidence of HIV infection only in 36 regions of Russia (43.4% of the total) exceeded 25 per 100,000 population. 23 regions of Russia with HIV incidence over 44 per 100,000 population are challenged with an exponential growth of HIV-TB cases. Implementation of a package of organizational measures implies close cooperation between TB and HIV control programs at all levels.

Keywords. Pulmonary tuberculosis; HIV-infection; HIV-TB co-infection; matrix analysis.


  1. Tuberculosis management: recommendations. 4-th edition. Geneva: WHO Regional Office for Europe. 2011. 183 p. [Internet]. 2011 [cited 2013 Feb 09]. Available from: http://whqlibdoc.who.int/publications/2011/9789244547830_rus.pdf (in Russian).
  2. Tompson AA, Striklend AJ. Strategic management. Skill of strategy development and implementation: Text book for higher educational institutions. Transl. from English. Zaytsev LG, Sokolova MI, eds. Moscow: Banki I birzhi, UNITI; 1998. 576 p.
  3. Tsybikova EB, Sabgayda TP. Epidemiology of tuberculosis associated with HIV. Zdravookhranenie Rossiyskoy Federatsii 2012;(6):7-11 (in Russian).
  4. Harries AD, Zachariah R, van Oosterhout JJ, Reid SD, Hosseinipour MC, Arendt V., et al. Diagnosis and management of antiretroviral-therapy failure in resource-limited settings in sub-Saharan Africa: challenges and perspectives. The Lancet Infectious Disease 2010;10(1):60-65.
  5. Holtz TH, Kabera G, Mthiyane T, Zingoni T, Nadesan S, Ross D, et al. Use of WHO-recommended algorithm to reduce mortality in seriously ill patients with HIV infection and smear-negative pulmonary tuberculosis in South Africa: an observational cohort study. The Lancet Infectious Disease 2011; 11(7):533-540.
  6. Rapid advice for antiretroviral therapy for HIV-related tuberculosis. Atlanta, GA, Centers for Disease Control and Prevention. [Internet]. 2007 [cited 2012 Dec 10]. Available from: http://www.cdc.gov/tb/publications/guidelines/TB_HIV_Drugs/PDF/tbhiv.pdf
  7. Uyei J, Coetzee D, Macinko J, Guttmacher S. Integrated delivery of HIV and tuberculosis services in sub-Saharan Africa: a systematic review. The Lancet Infectious Disease 2011;11(11):855-867.
  8. WHO Three I Meeting: Intensified case finding (ICF), Isoniazid preventive therapy (IPT) and TB Infection control (IC) for people living with HIV. Report of a joint WHO HIV/AIDS and TB department meeting. Geneva, WHO. [Internet]. 2008. [cited 2012 Dec 10]. Available from: http://www.who.int/hiv/pub/ meetings-reports/WHO_3Is_meeting_report.pdf

Views: 12356

Comments (1)
1. 21-04-2013 16:28
. .
Written by ( This e-mail address is being protected from spam bots, you need JavaScript enabled to view it ) (Guest)

Write Comment
  • Please keep the topic of messages relevant to the subject of the article.
  • Personal verbal attacks will be deleted.
  • Please don't use comments to plug your web site. Such material will be removed.
  • Just ensure to *Refresh* your browser for a new security code to be displayed prior to clicking on the 'Send' button.
  • Keep in mind that the above process only applies if you simply entered the wrong security code.

Code:* Code

Last Updated ( Thursday, 25 April 2013 )
< Prev   Next >
home contact search contact search